Senior Scientist, Analytical Development & Technology

Job description:

We are at the centre of the rapidly growing cell and gene therapy sector. We deliver life-changing therapies to patients, and so can you.

We are currently recruiting for a Senior Scientist to join the Analytical Development and Technologies group. The purpose of this role is to plan, execute and report experiments or analytical investigations and to support other members of the development team as needed to help the delivery of team goals and client work packages.

This is a maternity cover role up to approximately 12 months,

Your responsibilities in this role would be:

• Responsible for leading the development and qualification of cell-based vector potency assays with a particular focus on CAR-T products to support our clients.
• Act as an SME (Subject Matter Expert) in potency assays, including updating SOPs (Standard Operating Procedures), troubleshooting as required and as a reference in cases of assay investigations (i.e. deviations from procedure, change controls, etc.) and SME discussions with client teams.
• Innovation and development of new analytical assays, improvement, and optimisation of current analytical assays for lentiviral characterisation.
• Responsibility for the planning and execution of platform and complex assay development/ transfer studies independently.
• Ensuring robust technical transfer of methods cross-departmentally.
• Responsible for the completion of tasks in relation to their criticality.
• Support/ mentoring other scientists within the department.

We are looking for:

• Minimum BSc in a Biosciences or similar.
• Proven expertise in immunology and immunological assay development.
• Extensive laboratory experience in immunological methods including tissue culture, ELISA and luminescence assays and flow cytometry.
• Competency in data capture reporting and management systems.
• High level of familiarity with Microsoft Office.
• Knowledge of statistics and/ or AQBD/ DOE would be preferred.
• Knowledge in Virology and gene therapy products and experience working with viral vectors would be an advantage.
• Ability to work accurately in a busy and demanding environment, and to manage competing priorities.
• Credible and confident communicator (written & verbal) at all levels.
• Self-motivated with the ability to work proactively using own initiative.
• Demonstrates ability to work well in a team as well as independently.

About Us:

OXB is a quality and innovation-led viral vector CDMO with a mission to enable its clients to deliver life changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, we have more than 25 years of experience in viral vectors; the driving force behind the majority of gene therapies.

These capabilities are supported by robust quality-assurance systems, analytical methods and depth of regulatory expertise.

What’s in it for you:

• Highly competitive total reward packages
• Wellbeing programmes
• Development opportunities
• Welcoming, friendly, supportive colleagues
• A diverse and inclusive working environment
• Our values are: Deliver Innovation, Be Inspiring and Have Integrity
• State of the art laboratory and manufacturing facilities

We want you to feel inspired every day. We’re future-focused and our business is growing rapidly. We succeed together through passion, commitment and teamwork, and so can you.

Collaborate. Contribute. Change lives

We offer:

Oxford Biomedica is a quality and innovation-led viral vector CDMO that enables its clients to deliver life-changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, Oxford Biomedica has more than 25 years of experience in viral vectors, the driving force behind the majority of gene therapies.

This can be achieved either by directly administering the vector to the patient (often referred to as in vivo gene therapy), or by first introducing the genetic material to cells or tissue outside of the body, before administering the cells or tissue into the patient (often referred to as ex vivo gene therapy or gene-modified cell therapy).

Oxford Biomedica's world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods and depth of regulatory expertise.