Clinical Fellow - Advanced Immunotherapy & Cell Therapy Team
NHS Jobs Manchester
ORGANISATIONAL ARRANGEMENTSThis post is for 40 hours per week to provide medical support to the Advanced Immunotherapy and Cell Therapy Team (AICT) by primarily acting as co-investigator on early phase clinical trials. The role has the following accountabilities: AICT team led by Prof.
Fiona Thistlethwaite The interactions for this role include (but not limited to) the following:Advanced Immunotherapy and Cell Therapy Team Clinician, Clinical Fellows, Clinical Trial Pharmacists, Research Nurses, Healthcare Assistants, Clinical Trial Coordinators, Data Managers, Medical Secretaries, Clinical Trials Clerk, Translational Trial Facilitators, Investigator led study team, students.
Role PurposeThe Christie NHS Foundation Trust is one of the largest Cancer Centres in Europe covering a large population in North West England and seeing more than 14,000 new patients each year. The hospital is a designated teaching hospital of the University of Manchester and is the focal point of the Regional Cancer Network.
It is also a CRUK designated major cancer research centre and combined with the Cancer Research UK Manchester Institute and the University of Manchester comprises the Manchester Cancer Research Centre. The Advanced Immunotherapy and Cell Therapy Team is specifically designed to facilitate delivery of complex and innovative therapies emerging in oncology.
Facilities include inpatient beds, outpatient suites, trials pharmacy, laboratory and an administrative floor with short-term archiving, seminar room and monitoring rooms for external trials monitors. Clinical research and service work is closely integrated with laboratory research.
There are close links with the Cancer Research UK Manchester Institute which provide GCLP compliant laboratories. This together with the world class Biobank have strengthened and complemented this clinical development. This is an exceptional opportunity in the Advanced Immunotherapy and Cell Therapy Team.
We seek an ambitious, innovative individual to provide medical support to the consultants by primarily acting as co-investigator on a growing portfolio of early phase cell therapy and complex immunotherapy clinical trials. You will join a highly motivated and empowered workforce to increase research capacity and deliver innovative early phase research in compliance with Good Clinical Practice (ICH-GCP) and Trust policy.
You will be based within AICT, providing medical support to the consultants by primarily acting as co-investigator on the portfolio of complex trials. With consultant oversight, you will be responsible for seeing new referrals, follow-ups and for managing the patient throughout all aspects of their trial experience.
There will be opportunities to work with our broader Experimental Cancer Medicine Team (ECMT) which has a well-established and regular molecular tumour board meeting supporting both local and national studies. You will take an active role in these meetings gaining valuable experience in using these data to identify and define suitable trial options for patients.
You will have the opportunity to be involved in audit, writing papers and reviews and there is the potential to present research work at local, national, or international meetings. This is a 10 session non-training post (on the salary scale MN37, point dependent on experience) funded through The Christie NHS Foundation Trust for up to 2 years.
The role is suitable for individuals ideally having completed at least CMT training but those at the end of FY2 may also be considered. A more senior role may be available for those towards the end of, or having completed, their specialist oncology training who wish to gain further experience in experimental medicine and Phase I trials, including first-in-human trials, clinical pharmacology trials and translational research.
The position requires an ability to understand and deliver experimental clinical research, liaising across a range of clinical, academic and administrative staff throughout the Trust and with external organisations (pharmaceutical and biotech industry partners, academic institutions and other hospitals).
DUTIES AND RESPONSIBILITIESThe medical establishment provides 1-2 Consultant Medical Oncologists.DUTIES OF THE POST ROLE: The successful candidate will be recruited as a Senior Clinical Fellow in the Advanced Immunotherapy and Cell Therapy Team (AICT).
RESEARCH: A diverse range of clinical research trials are in progress and, following training, the post holder will be expected to participate in these studies as a co-/sub-investigator. These include cellular therapy and bispecific antibody early phase trials.You will be involved in managing all aspects of trial patients, across a diverse range of solid tumours, through new patient consultation, consent and screening patients and reviewing patients at follow-up appointments.
Primarily, patients are seen in the outpatient setting but with some inpatient cover. The appointee is required to attend 5 trial outpatient clinics per week (see indicative timetable).You will be expected to attend Safety Review Committee meetings (usually remotely) to discuss trial patients.
This will involve close liaison with the trial Principal Investigators, referring consultant body across the Trust and other members of the team. In addition, you will interface with external stakeholders such as CROs and pharmaceutical sponsors.You will be expected to attend monthly molecular tumour board meetings to discuss trial patients and to agree opportunities for patients to enroll in early phase trials.
PROTOCOLS: You will be expected to undertake the administrative duties associated with the care of their patients. You will be encouraged to harness opportunities to be involved in the development and planning of new studies. PROFESSIONAL DEVELOPMENT: You will maintain a level of continuing professional development consistent with the recommendations of the Royal College of Physicians.
Appropriate arrangements for study leave will be made in conjunction with colleagues. There is the potential to present research work and the post holder will be expected to be involved in audit, writing papers and reviews. You will also be required to undergo an annual appraisal.
TEACHING COMMITMENT:a) UndergraduateYou will be required to contribute to the undergraduate teaching of medical students on oncology topics.b) PostgraduateThrough collaboration with University of Manchester the team supports a busy postgraduate teaching programme and staff are often requested to lecture on relevant topics.
You will be expected to contribute actively to the education of junior doctors, specialty trainees and fellows on the team. You will also be expected to help in the training of nursing and multi-disciplinary staff in both in-patient and outpatient departments.
CLINICAL GOVERNANCE: You will be expected to participate in all relevant aspects of clinical governance, including maintaining up to date protocols, guidelines and clinical audit, under the supervision of the other consultants in the experimental cancer medicine team.
AUDIT: You will play a full role in clinical audit as a member of The Christie Medical Staff Committee. You will develop, supervise and deliver team audit projects. Continuing Professional DevelopmentThe Trust supports the requirements for continuing professional development (CPD) as laid down by the GMC and surgical colleges and is committed to providing time and financial support for these activities.
Role PlanningThis is a 10 session non-training specialty registrar funded through The Christie NHS Foundation Trust for an initial period of 1 year. Provisional Sessional Timetable for Senior Clinical Fellow in Experimental Medicine ___________________________________________________________ Proposed Sessional Activities Outpatient Clinics 4.0 Inpatient reviews 1.0 Research Administration 2.0 Teaching 1.0 Trial Teleconferences 0.5 Team Meeting 0.5 Audit/CPD 1.0 10 A Sessional Activity is 4 hours On call: there is no formal on-call commitment but if any on-call opportunities come up The Medical Staffing department will contact you.
Fiona Thistlethwaite The interactions for this role include (but not limited to) the following:Advanced Immunotherapy and Cell Therapy Team Clinician, Clinical Fellows, Clinical Trial Pharmacists, Research Nurses, Healthcare Assistants, Clinical Trial Coordinators, Data Managers, Medical Secretaries, Clinical Trials Clerk, Translational Trial Facilitators, Investigator led study team, students.
Role PurposeThe Christie NHS Foundation Trust is one of the largest Cancer Centres in Europe covering a large population in North West England and seeing more than 14,000 new patients each year. The hospital is a designated teaching hospital of the University of Manchester and is the focal point of the Regional Cancer Network.
It is also a CRUK designated major cancer research centre and combined with the Cancer Research UK Manchester Institute and the University of Manchester comprises the Manchester Cancer Research Centre. The Advanced Immunotherapy and Cell Therapy Team is specifically designed to facilitate delivery of complex and innovative therapies emerging in oncology.
Facilities include inpatient beds, outpatient suites, trials pharmacy, laboratory and an administrative floor with short-term archiving, seminar room and monitoring rooms for external trials monitors. Clinical research and service work is closely integrated with laboratory research.
There are close links with the Cancer Research UK Manchester Institute which provide GCLP compliant laboratories. This together with the world class Biobank have strengthened and complemented this clinical development. This is an exceptional opportunity in the Advanced Immunotherapy and Cell Therapy Team.
We seek an ambitious, innovative individual to provide medical support to the consultants by primarily acting as co-investigator on a growing portfolio of early phase cell therapy and complex immunotherapy clinical trials. You will join a highly motivated and empowered workforce to increase research capacity and deliver innovative early phase research in compliance with Good Clinical Practice (ICH-GCP) and Trust policy.
You will be based within AICT, providing medical support to the consultants by primarily acting as co-investigator on the portfolio of complex trials. With consultant oversight, you will be responsible for seeing new referrals, follow-ups and for managing the patient throughout all aspects of their trial experience.
There will be opportunities to work with our broader Experimental Cancer Medicine Team (ECMT) which has a well-established and regular molecular tumour board meeting supporting both local and national studies. You will take an active role in these meetings gaining valuable experience in using these data to identify and define suitable trial options for patients.
You will have the opportunity to be involved in audit, writing papers and reviews and there is the potential to present research work at local, national, or international meetings. This is a 10 session non-training post (on the salary scale MN37, point dependent on experience) funded through The Christie NHS Foundation Trust for up to 2 years.
The role is suitable for individuals ideally having completed at least CMT training but those at the end of FY2 may also be considered. A more senior role may be available for those towards the end of, or having completed, their specialist oncology training who wish to gain further experience in experimental medicine and Phase I trials, including first-in-human trials, clinical pharmacology trials and translational research.
The position requires an ability to understand and deliver experimental clinical research, liaising across a range of clinical, academic and administrative staff throughout the Trust and with external organisations (pharmaceutical and biotech industry partners, academic institutions and other hospitals).
DUTIES AND RESPONSIBILITIESThe medical establishment provides 1-2 Consultant Medical Oncologists.DUTIES OF THE POST ROLE: The successful candidate will be recruited as a Senior Clinical Fellow in the Advanced Immunotherapy and Cell Therapy Team (AICT).
RESEARCH: A diverse range of clinical research trials are in progress and, following training, the post holder will be expected to participate in these studies as a co-/sub-investigator. These include cellular therapy and bispecific antibody early phase trials.You will be involved in managing all aspects of trial patients, across a diverse range of solid tumours, through new patient consultation, consent and screening patients and reviewing patients at follow-up appointments.
Primarily, patients are seen in the outpatient setting but with some inpatient cover. The appointee is required to attend 5 trial outpatient clinics per week (see indicative timetable).You will be expected to attend Safety Review Committee meetings (usually remotely) to discuss trial patients.
This will involve close liaison with the trial Principal Investigators, referring consultant body across the Trust and other members of the team. In addition, you will interface with external stakeholders such as CROs and pharmaceutical sponsors.You will be expected to attend monthly molecular tumour board meetings to discuss trial patients and to agree opportunities for patients to enroll in early phase trials.
PROTOCOLS: You will be expected to undertake the administrative duties associated with the care of their patients. You will be encouraged to harness opportunities to be involved in the development and planning of new studies. PROFESSIONAL DEVELOPMENT: You will maintain a level of continuing professional development consistent with the recommendations of the Royal College of Physicians.
Appropriate arrangements for study leave will be made in conjunction with colleagues. There is the potential to present research work and the post holder will be expected to be involved in audit, writing papers and reviews. You will also be required to undergo an annual appraisal.
TEACHING COMMITMENT:a) UndergraduateYou will be required to contribute to the undergraduate teaching of medical students on oncology topics.b) PostgraduateThrough collaboration with University of Manchester the team supports a busy postgraduate teaching programme and staff are often requested to lecture on relevant topics.
You will be expected to contribute actively to the education of junior doctors, specialty trainees and fellows on the team. You will also be expected to help in the training of nursing and multi-disciplinary staff in both in-patient and outpatient departments.
CLINICAL GOVERNANCE: You will be expected to participate in all relevant aspects of clinical governance, including maintaining up to date protocols, guidelines and clinical audit, under the supervision of the other consultants in the experimental cancer medicine team.
AUDIT: You will play a full role in clinical audit as a member of The Christie Medical Staff Committee. You will develop, supervise and deliver team audit projects. Continuing Professional DevelopmentThe Trust supports the requirements for continuing professional development (CPD) as laid down by the GMC and surgical colleges and is committed to providing time and financial support for these activities.
Role PlanningThis is a 10 session non-training specialty registrar funded through The Christie NHS Foundation Trust for an initial period of 1 year. Provisional Sessional Timetable for Senior Clinical Fellow in Experimental Medicine ___________________________________________________________ Proposed Sessional Activities Outpatient Clinics 4.0 Inpatient reviews 1.0 Research Administration 2.0 Teaching 1.0 Trial Teleconferences 0.5 Team Meeting 0.5 Audit/CPD 1.0 10 A Sessional Activity is 4 hours On call: there is no formal on-call commitment but if any on-call opportunities come up The Medical Staffing department will contact you.
Indicative Clinical Timetable Monday Tuesday Wednesday Thursday Friday Cell Therapy Clinic Team Meeting Audit/CPD Disease specific Clinic Research Admin Cell Therapy Clinic Trial Teleconferences Audit/CPD Phase I new patient Clinic Inpatient reviews Research Admin Teaching
Outcomes First GroupRawtenstall, 17 mi from Manchester
Does working 4 days a week but with FULL pay sound like a dream?!***
**It doesnt have to be! Have a better worklife balance and come and work
for Outcomes First Group!**
**Job Title: Lead Clinician**
**Location: Belmont Secondary School...
NHS JobsManchester
To find out more about the key responsibilities and the specific skills and experience youll need, take a look at the Job Description & Person Specification attachments under the Supporting Documents heading. So that youre even more equipped to make...
Wrightington, Wigan & Leigh NHS Foundation TrustWigan, 17 mi from Manchester
application how you match all points, providing examples of experience, understandingand transferable skills.
The Health Care Operations Department are looking to recruit a Clinic Prep Clerk (37.5hrs) within the Prep Team based at the RAEI site, Wigan...