[ref. o91090101] Laboratory Research Scientist
Laboratory Research Scientist
Short summary
An exciting opportunity for a motivated research technician/ laboratory research scientist to join Kinases and Brain Development laboratory https://www.crick.ac.uk/research/labs/sila-ultanir at the Francis Crick Institute, London, UK.
Ultanir lab is recruiting a Laboratory Research Scientist (LRS) role. The LRS will collaborate with members of the lab and help with human iPSC cultures, including their maintenance and characterization. She/he will also receive training to assist with mass spectrometry experiments.
Dr Ultanir’s laboratory focuses on the role of protein kinases in neuronal development and function. Kinases regulate numerous cellular processes by phosphorylating their substrates and altering their function. CDKL5 is a brain enriched serine/threonine kinase.Loss of function mutations of CDKL5 cause a severe neurodevelopmental disorder with early-onset seizures and profound developmental delays, termed CDKL5 deficiency disorder (CDD). Our lab’s aim is to understand the roles of CDKL5 in the brain and to reveal how loss of CDKL5 leads to neuronal pathology.
Key Responsibilities
The role of a Laboratory Research Scientist in the Crick is diverse and rewarding. Typical activities include:
- Collaborating with other lab members on/Assisting other lab members with/ research projects.
- Providing experimental or technical support to other lab members.
- Providing technical expertise/ input for the development, refinement and troubleshooting of relevant methodologies.
- Participating in academic activities, including group meetings and journal clubs, seminars, and scientific meetings.
- Organisation and management of the laboratory
- Differentiate and maintain iPSC derived neuronal cultures
- Maintain rat astrocyte cultures
- Immunostainings and imaging of neurons in culture.
- Cloning, transfection, viral infections of neurons in culture.
- Perform multi-electrode array recordings and data analysis.
Find out what benefits the Crick has to offer:
For more information on our great pay and benefits package please click here: https://www.crick.ac.uk/careers-and-study/life-at-the-crick/pay-and-benefits
Equality, Diversity & Inclusion:
We welcome applications from all backgrounds. We are committed to providing equal employment opportunities, regardless of ethnicity, nationality, gender, sexual orientation, gender identity, religion, pregnancy, age, disability, or civil partnership, marital or family status.We particularly welcome applications from people who are Minority Ethnic as they are currently underrepresented in the Crick at this level.
Diversity is essential to excellence in scientific endeavour. It increases breadth and perspective, leading to more innovation and creativity. We want the Crick to be a place where everyone feels valued and where diversity is celebrated and seen as part of the foundation for our Institute’s success.
The Crick is committed to creating equality of opportunity and promoting diversity and inclusivity. We all share in the responsibility to actively promote dignity, respect, inclusivity and equal treatment and it is our aim to ensure that these principles are reflected and implemented in all strategies, policies and practices.
Read more on our website: https://www.crick.ac.uk/careers-and-study/life-at-the-crick/equality-diversity-and-inclusion