Senior / Principal Medical Director Alzheimers Disease Clinical Development
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The Position
We advance science so that we all have more time with the people we love.
Our Clinical Development team has a fantastic opportunity for a Senior/Principal Medical Director to join the neurology franchise to support late-stage clinical studies. The key focus for this role would be on Trontinemab which is the first anti-amyloid antibody in trials to use brain-shuttle technology, which Roche and other companies have been developing for years.
The Senior/Principal Medical Director leads the development of the Clinical Development (CD) strategy and is responsible for developing the CD plan and ensuring effective and efficient execution for assigned molecule(s)/indication(s). Principal Medical Directors are also expected to contribute CD expertise to the specific therapeutic (i.e. Neurology - Alzheimer’s disease) strategies and plans, including enhanced biomarkers and advanced imaging analytics development.
THE OPPORTUNITY- You will be responsible for the development and operational alignment of the Clinical Development Plan (CDP) for assigned molecule(s)/indication(s); You will act as the CDP lead and/or supervise the development of study analytics & data management plans.
- You will collaborate with a variety of internal/external partners & stakeholders, as well as multidisciplinary internal groups, including business development, research, commercial, legal, etc.
- You may participate in meetings, reviews, discussions and other interactions regarding early development/Phase I studies to provide clinical science input & guidance; including reviewing and providing late stage input to Phase I & II protocols.
- You will lead or oversee others in development of briefing packages by providing clinical science information and input; Leads or oversees others in development of responses to HA questions by providing clinical science information and input; Leads or oversees others in health authority (HA) interactions.
- You will play a lead role in educating others internally and externally on relevant clinical developments as these may implicate the assigned therapeutic area’s CDP strategies, plans and programs; You will help research and other groups to ensure consistency of scientific and late-development strategies with target label claims and corporate goals, including the ability to perform clinical assessments on relevant drug discovery projects.
- MD Neurologist ideally specializing in geriatrics
- Strong presence and relationships with KOLs in the field of neurodegenerative medicine
- You have 8+ years of pharma/biotech R&D experience. Strong experience in late-stage drug development is essential.
- Health Authority Interaction experience for pivotal trials in the US and Globally
- You have strong interpersonal skills: Outstanding interpersonal, verbal, and written communication and influencing skills, proven ability to influence internal partners and stakeholders, thought leaders, national advocacy organizations, national standard-setting bodies, and other relevant external parties. Seamlessly collaborates with colleagues/other parts of the organization.
If you are a Neurologist with experience in Alzheimer’s disease drug development and would like to be a part of a team that is committed to delivering transformational medicines to patients, we would love to hear from you.
Who we are
At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.
Our UK Pharmaceutical head office is situated in Welwyn Garden City, Hertfordshire, with beautiful countryside surrounding the area. Supported by major motorways & airports as well as being a 30 minute train ride to London, access is easy. Our award-winning office, known as Hexagon Place, was opened in 2005 and provides a modern, flexible working environment with facilities that are second-to-none.Around 2,000 people work at our Welwyn office in Global Early Development (pRED), Global Product Development (PD), Commercial (Rx) and our Corporate functions.
Roche offer a competitive salary plus the excellent benefits you would expect from a blue-chip organisation. There is a fully equipped gym on-site, a library and information centre, and an active sports and social club. We also have a subsidised staff restaurant providing foods to cater for every taste throughout the day.At the heart of the building is an informal meeting area known as The Street which features a coffee shop, snack machine and cashpoint. A second building on-site, called The Hub, contains modern meeting room and conference facilities. Roche promotes personal well-being and work-life balance.
Therefore, flexible working options will be considered for all roles at Roche UK. Roche is committed to creating a diverse & inclusive environment. The statements herein are intended to describe the general nature and level of work being performed by employees, and are not to be construed as an exhaustive list of responsibilities, duties, and skills required of personnel so classified.
Furthermore, they do not establish a contract for employment and are subject to change at the discretion of Roche.
The statements herein are intended to describe the general nature and level of work being performed by employees, and are not to be construed as an exhaustive list of responsibilities, duties, and skills required of personnel so classified. Furthermore, they do not establish a contract for employment and are subject to change at the discretion of Roche Products Ltd.At Roche Products we believe diversity drives innovation and we are committed to building a diverse and flexible working environment. All qualified applicants will receive consideration for employment without regard to race, religion or belief, sex, gender reassignment, sexual orientation, marriage and civil partnership, pregnancy and maternity, disability or age.
We recognise the importance of flexible working and will review all applicants’ requests with care. At Roche difference is valued and we are proud to be an equal opportunity employer where you are encouraged to bring your whole self to work.