Clinical Research Fellow in Hepatology Trials | Imperial College Healthcare NHS Trust

The Imperial College Healthcare NHS Trust’s Hepatology Clinical Research Facility (CRF) for clinical research and investigation is based on the 10thFloor of the Queen Elizabeth Queen Mother Wing at St Mary’s Campus and provides a state of the art, designated area for hepatology academics and hepatology clinicians to perform clinical research projects involving both patients with liver conditions and healthy volunteers.

The postwill specifically help Principal Investigators and the research nursing team with patient recruitment into commercially sponsored clinical drug trials (alcohol, hepatitis, and fatty liver) and the ongoing management of patients according to the study protocols.

In undertaking this role, the Clinical Research Fellow will gain experience in the management of clinical trials and novel therapeutics in chronic liver disease.

The post is initially for 6 months, but will be renewable, and is suitable for a junior grade doctor (FY2 – FY5) who has a minimum of 1 year’s post registration, recent experience of working in the NHS in a medical post, and who is looking to learn and develop clinical research skills.GMC registration and licence to practice are essential.

• Support the timely delivery of clinical studies, in-line with the requirements of sponsors, GCP (Good Clinical Practice), and other appropriate guidelines and regulations
• Provide medical assessment and cover for selected studies in the Hepatology CRF working alongside other clinical teams

• Ensure that patients/volunteers in assigned studies give fully informed consent in writing before commencing a study
• Assess and interpret safety and clinical data from assigned studies, e.g. vital signs, ECG's, laboratory tests, adverse events etc.
• Follow up and report Adverse Events as necessary. Communicate safety issues to the Principal Investigator, report Serious Adverse Events in accordance with Good Clinical Practice
• Ensure that all clinical activities within the CRF are conducted in accordance with approved Standard Operating Procedures (SOPs)
• Attend clinics and provide clinical cross cover where appropriate
• Be responsible for specific study-related medical decisions as agreed with the Principal Investigators
• Assess the eligibility of patient referrals for trials, and maintain and update a screening list

You’ll get an experience like no other and will fast forward your career. Benefits include career development, flexible working and wellbeing, staff recognition scheme. Make use of optional benefits including Cycle to work, car lease schemes, season ticket loan or membership options for onsite leisure facilities.

The successful applicant may have contact with patients and service users and as part of our pre-employment checks and risk assessments, we will ask all candidates to confirm whether or not they have been fully vaccinated or have a medical exemption.

As part of our continued response to Covid19 we are still conducting the majority of our interviews virtually.

We are committed to equal opportunities and improving the working lives of our staff and will consider applications to work flexibly, part-time or job share. Please talk to us at interview.

• Support the delivery of clinical studies, in-line with requirements of sponsors, GCP (Good Clinical Practice), and other appropriate regulations
• Provide medical assessment and cover for studies in the Hepatology CRF
• Perform clinical trial procedures (clinical examinations, insertion of intravenous lines, assessment of adverse events and management of medical emergencies, etc)
• Ensure patients give full informed consent before starting a study
• Assess and interpret safety and clinical trial data (vital signs, ECG's, laboratory tests, AEs etc).
• Follow up and report AEs. Communicate safety issues to the Principal Investigator, report SAEs in accordance with Good Clinical Practice
• Attend clinics and provide clinical cross cover where appropriate
• Be responsible for specific study-related medical decisions as agreed with the Principal Investigator
• Assess the eligibility of patients for trials, maintain and update screening lists
• Accept delegated responsibility to ensure that trials in the Hepatology CRF are carried outsafely and in compliance with the protocol
• Evaluate and manage chronic adverse drug reactions and manage acute toxicological emergencies under the supervision of the consultants in charge
• Maintain accurate and accessible research records and medical notes
• Participate in research meetings, study review meetings and meetings with Principal Investigators and study sponsors
• Any other duties as may be deemed reasonable by senior clinical staff of the Hepatology CRF

This advert closes on Tuesday 19 Nov 2024